Beat cream cheese, egg, sugar, flour and vanilla extract in large mixer bowl until smooth; spread mixture over graham cracker crust.
Combine Harvest Apples, caramel topping and cinnamon in small bowl; gently spoon over cream cheese mixture to keep two distinct layers.
Bake in preheated 375°F. oven for 40 to 45 minutes or until apple mixture bubbles up around edges of pie. Cool on wire rack. Serve at room temperature; promptly chill leftover pie.